Nogo B receptor Recombinant Rabbit mAb, Unconjugated
Artikelnummer:
BWT-BS47300
Hersteller Artikelnummer:
BS47300
Alternativnummer:
BWT-BS47300-50UL,BWT-BS47300-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
A synthetic peptide of human Nogo B receptor
Konjugation:
Unconjugated
Alternative Synonym:
NgBR, MRD55, CDG1AA, C6orf68, TANGO14, MGC:7199
This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X. [provided by RefSeq, May 2017]
Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Application Verdünnung:
WB: 1:1000
Anwendungsbeschreibung:
IgG
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
