Synapsin I (phospho-S9) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS4802
Hersteller Artikelnummer:
BS4802
Alternativnummer:
BWT-BS4802-50UL,BWT-BS4802-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Synthetic phosphopeptide derived from human Synapsin I around the phosphorylation site of Serine 9.
Konjugation:
Unconjugated
Alternative Synonym:
Synapsin-1, Synapsin 1, Synapsin1, Brain protein 4.1, Synapsin I, SYN1
Synapsin I is a member of the synapsin family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations of the Synapsin I gene may be associated with X linked disorders with primary neuronal degeneration such as Rett syndrome.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Anwendungsbeschreibung:
p-Synapsin I (S9) polyclonal antibody detects endogenous levels of Synapsin I protein when phosphorylated at Ser9.
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