PI3-Kinase catalytic subunit alpha Recombinant Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: PI3-Kinase catalytic subunit alpha Recombinant Rabbit mAb, Unconjugated
• Artikelnummer: BWT-BS48058
• Hersteller Artikelnummer: BS48058
• Alternativnummer: BWT-BS48058-50UL,BWT-BS48058-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IP, WB
• Spezies Reaktivität: Mouse, Rat
• Immunogen: Recombinant protein of mouse PI 3 Kinase catalytic subunit alpha
• Konjugation: Unconjugated
• Alternative Synonym: p110, caPI3K, p110alpha, 6330412C24Rik

Produktbeschreibung

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins.

Produkteigenschaften

• Molekulargewicht: 110 kDa
• UniProt: P42337
• Reinheit: Affinity Purification
• Formulierung: Store at -20C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:1000<br />IP: 1:20
• Anwendungsbeschreibung: IgG