beta-1,3-Gal-T6 (beta-1,3-galactosyltransferase 6), also known as galactosyltransferase II or GAG GalTII, is a 329 amino acid protein belonging to the glycosyltransferase 31 family. beta-1,3-Gal-T6 is involved in several glycan metabolism pathways. With manganese as a cofactor, beta-1,3-Gal-T6 catalyzes the transfer of galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. beta-1,3-Gal-T6 has a preference for galactose-beta-1,4-xylose found in the linker region of chondroitin sulfate, heparan sulfate and other glycosaminoglycans, but does not have activity towards substrates with terminal galactosamine or glucosamine residues. Ubiquitously expressed, beta-1,3-Gal-T6 is a single-pass type II membrane protein localized to the Golgi stack membrane.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000
Anwendungsbeschreibung:
B3GALT6 polyclonal antibody detects endogenous levels of B3GALT6 protein.
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