A synthetic peptide corresponding to residues in Human B4GALT6
Konjugation:
Unconjugated
Alternative Synonym:
Beta-1,4-galactosyltransferase 6, Beta-1,4-GalTase 6, Beta4Gal-T6, b4Gal-T6, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6 , Including the following 1 domains:Glucosylceramide beta-1,4-galactosyltransferase, Lactosylceramide synthase, LacCer synthase, UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase, B4GALT6
beta-1,4-galactosyltransferases (beta-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a beta-1,4 linkage to an acceptor sugar. There are seven members of the beta-1,4-Gal-T family, all of which are directed to the Golgi apparatus through a hydrophobic sequence at the N-terminus. beta-1,4-Gal-T6, also known as B4GALT6, is a 382 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and belongs to the beta-1,4-galactosyltransferase family. Expressed at high levels in adrenal gland and brain and present at lower levels in lung, liver and colon, beta-1,4-Gal-T6 uses magnesium or zinc to catalyze the UDP-dependent biosynthesis of glycosphingolipids. The gene encoding beta-1,4-Gal-T6 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000
Anwendungsbeschreibung:
B4GALT6 polyclonal antibody detects endogenous levels of B4GALT6 protein.
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