A synthetic peptide corresponding to residues in Human ARSD.
Konjugation:
Unconjugated
Alternative Synonym:
Arylsulfatase D, ASD, ARSD
Arylsulfatase D, also known as ARSD, is a 593 amino acid protein that localizes to the lysosome and belongs to the sulfatase family of bone and cartilage matrix proteins. Existing as three alternatively spliced isoforms which are expressed in liver, pancreas, kidney, heart, brain, lung and placenta, Arylsulfatase D uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turners syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:1000
Anwendungsbeschreibung:
ARSD polyclonal antibody detects endogenous levels of ARSD protein.
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