FYB polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS62547
Artikelname: FYB polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS62547
Hersteller Artikelnummer: BS62547
Alternativnummer: BWT-BS62547-50UL,BWT-BS62547-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to Human FYB.
Konjugation: Unconjugated
Alternative Synonym: ADAP, p120/p130, FYB1, FYB, SLAP130, Adhesion and degranulation promoting adaptor protein,, Fyb, FYB-120/130, FYN binding protein, FYN-binding protein, FYN-T-binding protein, SLAP-130, SLAP130, SLP-76-associated phosphoprotein
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
Molekulargewicht: ~ 110 kDa
UniProt: O15117
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB:1:500~1:1000
Anwendungsbeschreibung: FYB polyclonal antibody detects endogenous levels of FYB protein.