MKK3 (Phospho-T222) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: MKK3 (Phospho-T222) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS64557
• Hersteller Artikelnummer: BS64557
• Alternativnummer: BWT-BS64557-50UL,BWT-BS64557-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Zebrafish
• Immunogen: Synthetic phosphopeptide derived from human MKK3 around the phosphorylation site of Threonine 222.
• Konjugation: Unconjugated
• Alternative Synonym: Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MAPK/ERK kinase 3, MEK 3, Stress-activated protein kinase kinase 2, SAPK kinase 2, SAPKK-2, SAPKK2, MAP2K3, MEK3, MKK3, PRKMK3, SKK2

Produktbeschreibung

The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinaseegulatory threonine and tyrosine residues present in thehr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6hosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Produkteigenschaften

• Molekulargewicht: ~ 40 kDa
• UniProt: P46734
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
• Anwendungsbeschreibung: MKK3 (Phospho-T222) polyclonal antibody detects endogenous levels of MKK3 protein only when phosphorylated at Thr222.