Cyclophilin B monoclonal Antibody, Unconjugated, Mouse
Artikelnummer:
BWT-BS65500M
Hersteller Artikelnummer:
BS65500M
Alternativnummer:
BWT-BS65500M-50UL,BWT-BS65500M-100UL
Hersteller:
Bioworld Technology
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
KLH conjugated synthetic peptide derived from human Cyclophilin B
Konjugation:
Unconjugated
Alternative Synonym:
Cphn 2, Cphn2, CyP 20b, CYP S1, CYP-S1, CYPB, MGC14109, MGC2224, peptidyl prolyl cis trans isomerase B, Peptidyl prolyl cis trans isomerase B precursor, Peptidyl-prolyl cis-trans isomerase B precursor, Peptidylprolyl isomerase B, PPIase, PPIB, Rotamase, S cyclophilin, SCYLP, PPIB_HUMAN.
The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.
