Bovine, Canine, Equine, Human, Mouse, Porcine, Rat
Immunogen:
KLH conjugated synthetic peptide derived from human RNF43:401-500/783
Konjugation:
Unconjugated
Alternative Synonym:
RNF124, Ring finger protein 43, URCC, RNF43_HUMAN, E3 ubiquitin-protein ligase RNF43, RING finger protein 43.
RNF43 is a probable E3 ubiquitin-protein ligase that promotes cell growth and is upregulated in colon cancer. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
