Acetyl Coenzyme A Carboxylase Polyclonal Antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS65613
Artikelname: Acetyl Coenzyme A Carboxylase Polyclonal Antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS65613
Hersteller Artikelnummer: BS65613
Alternativnummer: BWT-BS65613-50UL,BWT-BS65613-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC-P
Spezies Reaktivität: Bovine, Human, Monkey, Mouse, Rat
Immunogen: KLH conjugated synthetic peptide derived from human Acetyl Coenzyme A Carboxylase 1/2:2307-2355/2458
Konjugation: Unconjugated
Alternative Synonym: Acetyl Coenzyme A Carboxylase, ACAS2, AceCS, Acetate CoA ligase, Acetyl CoA synthetase, Acetyl coenzyme A synthetase cytoplasmic, Acetyl-CoA synthetase, ACS, ACSA, ACSS2, Acyl activating enzyme, Acyl CoA synthetase short chain family member 2, EC 6.2.1.1, MYH7B, ACAC, ACACB, ACC alpha, ACC beta, ACC1, ACC2, ACCA, ACCB, Acetyl CoA carboxylase 1, Acetyl CoA carboxylase 2, Acetyl CoA carboxylase alpha, Acetyl CoA carboxylase beta, Biotin carboxylase, COA1, COA2, HFA1, ACACB_HUMAN, ACACA_HUMAN, Acetyl Coenzyme A Carboxylase, Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Acetyl-CoA carboxylase 265, ACC-alpha, ACC-beta.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5 sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Molekulargewicht: 265kD
UniProt: O00763
Reinheit: affinity purified by Protein A
Formulierung: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Application Verdünnung: IHC-P=1:100-500
Anwendungsbeschreibung: Acetyl Coenzyme A Carboxylase Polyclonal Antibody detects endogenous levels of Acetyl Coenzyme A Carboxylase protein.