KLH conjugated synthetic peptide derived from human Cux2:1001-1085/1486
Konjugation:
Unconjugated
Alternative Synonym:
CDP2, Cut like homeobox 2, Cut-like 2, CUTL2, CUX2, Homeobox protein cut-like 2, Homeobox protein cux 2, Homeobox protein Cux-2, KIAA0293, CUX2_HUMAN.
Cux2 is a marker for cortical subpopulations. Cux2 is an orthologue of the Drosophila cut gene, which encodes a homeodomain protein involved in neuronal specification. During cortical development Cux2 identifies two subpopulations with different spatial origins, migratory behaviours and phenotypic characteristics: (i) a population of interneurons, which invades the pallium from the subpallium, and (ii) a neuronal population produced in the pallium around embryonic day 11.5, which divides in the SVZ and accumulates in the intermediate zone (IZ). Subsequently, Cux2 is a marker of upper cortical layers.
