KLH conjugated synthetic peptide derived from human ERN2:465-550/926
Konjugation:
Unconjugated
Alternative Synonym:
IRE1b, Endoplasmic reticulum to nucleus signaling 2, ER to nucleus signalling 2, ERN 2, Ern1, hIRE2p, Inositol requiring 1 beta, Inositol requiring protein 2, Ire1, Ire1 beta, IRE1 S. cerevisiae homolog of, IRE2, Serine/threonine protein kinase/endoribonuclease IRE2, ERN2_HUMAN.
ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins.
