Wilms Tumor Protein Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Wilms Tumor Protein Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS65971
• Hersteller Artikelnummer: BS65971
• Alternativnummer: BWT-BS65971-50UL,BWT-BS65971-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IHC-P
• Spezies Reaktivität: Bovine, Canine, Gallus, Human, Mouse, Porcine, Rat, Sheep
• Immunogen: KLH conjugated synthetic peptide derived from human Wilms Tumor Protein:301-400/449
• Konjugation: Unconjugated
• Alternative Synonym: WIT 2, WT 1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1, Wilms Tumor, Wilms tumor protein, Wilms tumor gene, Wilms tumor protein, WIT2, WT, WT1, WT-1, WT1_HUMAN, WT33.

Produktbeschreibung

Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5-CGCCCCCGC-3. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Produkteigenschaften

• Molekulargewicht: 55kDa
• UniProt: P19544
• Reinheit: affinity purified by Protein A
• Formulierung: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Anwendungsbeschreibung

• Application Verdünnung: IHC-P=1:100-500 Flow-Cyt=1ug/test
• Anwendungsbeschreibung: Wilms Tumor Protein Polyclonal Antibody detects endogenous levels of Wilms Tumor Protein protein.