Bovine, Canine, Equine, Human, Mouse, Porcine, Rat
Immunogen:
KLH conjugated synthetic peptide derived from human Estrogen Related Receptor alpha:101-200/423
Konjugation:
Unconjugated
Alternative Synonym:
Estrogen Related Receptor alpha, ERR-alpha, ERR alpha, ERRalpha, ERR alpha, Err 1, ERR a, ERR alpha, ERR-alpha, Err1, ERR1_HUMAN, ERRa, ERRalpha, ESRL 1, ESRL1, ESRR A, Esrra, Estrogen receptor like 1, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen related receptor alpha, Estrogen-related receptor alpha, Estrra, Nr3b1, Nuclear receptor subfamily 3 group B member 1, Steroid hormone receptor ERR1.
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5-TNAAGGTCA-3. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
