Bovine, Canine, Equine, Gallus, Human, Mouse, Porcine, Rat, Sheep
Immunogen:
KLH conjugated synthetic peptide derived from human Retinoic acid induced 17:51-150/1067
Konjugation:
Unconjugated
Alternative Synonym:
Zinc finger MIZ domain-containing protein 1, MIZ, PIAS like protein hZimp10, PIAS like protein on chromosome 10, PIAS like protein Zimp10, PIAS-like protein Zimp10, RAI 17, RAI17, RAI-17, Retinoic acid induced 17, Retinoic acid induced protein 17, Retinoic acid-induced protein 17, TRAFIP10, Zimp10, Zinc finger containing Miz1 PIAS like protein on chromosome 10, Zinc finger MIZ domain-containing protein 1, Zinc finger MIZ-type containing 1, Zmiz1, ZMIZ1_HUMAN, hZIMP10, KIAA1224.
Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. Tissue specificity:Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.