Factor IX / F9 polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS6599
Hersteller Artikelnummer:
BS6599
Alternativnummer:
BWT-BS6599-50UL,BWT-BS6599-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Recombinant fusion protein of human IX / F9(NP_000124.1).
Konjugation:
Unconjugated
Alternative Synonym:
F9,F9 p22,FIX,HEMB,P19,PTC,THPH8,F9p22
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200
Anwendungsbeschreibung:
Polyclonal Antibodies
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
