A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MADCAM1 (NP_570116.2).
Konjugation:
Unconjugated
Alternative Synonym:
MADCAM1, MACAM1
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB 1:200 - 1:1000 IHC 1:50 - 1:100
Anwendungsbeschreibung:
MADCAM1 polyclonal antibody detects endogenous levels of MADCAM1 protein.
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