FPRL1 Polyclonal Antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS66133
- Bilder (0)
| Artikelname: | FPRL1 Polyclonal Antibody, Unconjugated, Rabbit |
| Artikelnummer: | BWT-BS66133 |
| Hersteller Artikelnummer: | BS66133 |
| Alternativnummer: | BWT-BS66133-50UL,BWT-BS66133-100UL |
| Hersteller: | Bioworld Technology |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | KLH conjugated synthetic peptide derived from human FPRL1: 51-150/351 |
| Konjugation: | Unconjugated |
| Alternative Synonym: | ALXR, FMLP R I, FMLP R II, FMLP related receptor I, FMLP-R-I, FMLP-R-II, FMLP-related receptor I, FMLPX, Formyl peptide receptor 2, Formyl peptide receptor like 1, Formyl peptide receptor related, Formyl peptide receptor-like 1, FPR 2, FPR2, FPR2_HUMAN, FPR2A, FPRH 1, FPRH 2, FPRH1, FPRH2, FPRL 1, FPRL1, HM63, Lipoxin A4 receptor, LXA4 receptor, LXA4R, N-formyl peptide receptor 2, RFP |
| FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries. |
| Molekulargewicht: | ~ 48 kDa |
| UniProt: | P25090 |
| Reinheit: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Formulierung: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Application Verdünnung: | WB: 1:500-1:2000 ELISA: 1:5000-1:10000 |
| Anwendungsbeschreibung: | FPRL1 Polyclonal Antibody detects endogenous levels of FPRL1 protein. |
Produktgarantie und fachkundiger Support
