CaIPLA2 Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: CaIPLA2 Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS66138
• Hersteller Artikelnummer: BS66138
• Alternativnummer: BWT-BS66138-50UL,BWT-BS66138-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: KLH conjugated synthetic peptide derived from human CaIPLA2/PLA2G6: 651-750/806
• Konjugation: Unconjugated
• Alternative Synonym: group VI iPLA2, 85 kDa calcium independent phospholipase A2, 85 kDa calcium-independent phospholipase A2, CaI PLA2, CaI-PLA2, CaIPLA2, Calcium independent phospholipase A2, Cytosolic calcium independent phospholipase A2, Group VI phospholipase A2, GVI, GVI PLA2, INAD1, iPLA(2)beta, iPLA2, IPLA2 VIA, iPLA2beta, NBIA2A, NBIA2B, PA2G6_HUMAN, PARK14, Patatin like phospholipase domain containing 9, Patatin like phospholipase domain containing protein 9, Phospholipase A2 calcium independent, Phospholipase A2 calcium independent group VI A, Phospholipase A2 group VI, Phospholipase A2 group VI cytosolic calcium independent, PLA2, PLA2G6, PNPLA9, PLPL9_HUMAN

Produktbeschreibung

Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.

Produkteigenschaften

• Molekulargewicht: ~ 90 kDa
• UniProt: O60733
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500-1:2000 ELISA: 1:5000-1:10000 IHC: 1:100-1:500 IF: 1:100-1:500
• Anwendungsbeschreibung: CaIPLA2 Polyclonal Antibody detects endogenous levels of CaIPLA2 protein.