PIAS3 polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS71897
Artikelname: PIAS3 polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS71897
Hersteller Artikelnummer: BS71897
Alternativnummer: BWT-BS71897-50UL,BWT-BS71897-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PIAS3.
Konjugation: Unconjugated
Alternative Synonym: PIAS3,ZMIZ5
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
Molekulargewicht: ~ 68 kDa
UniProt: Q9Y6X2
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB,1:500 - 1:1000|IHC,1:100 - 1:200
Anwendungsbeschreibung: PIAS3 polyclonal antibody detects endogenous levels of PIAS3 protein.