CBFA2T3 polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS72475
Artikelname: CBFA2T3 polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS72475
Hersteller Artikelnummer: BS72475
Alternativnummer: BWT-BS72475-50UL,BWT-BS72475-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human CBFA2T3(NP_005178.4).
Konjugation: Unconjugated
Alternative Synonym: CBFA2T3,ETO2,MTG16,MTGR2,RUNX1T3,ZMYND4
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16,21)(q24,q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5-region of the runt-related transcription factor 1 gene fused to the 3-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Molekulargewicht: 75KDa
UniProt: O75081
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB,1:500 - 1:2000
Anwendungsbeschreibung: Polyclonal Antibodies