BIG 3, Big, BIG3, BMP2 induced 3 kb gene protein, BMP2 induced gene, 3-KB, BMP2-induced 3-kb gene protein, MGC114572, OTTHUMP00000162494, SWD 3, SWD3, SWD3 Set1c WD40 repeat protein homolog, WD repeat containing protein 5, WD repeat domain 5, WD repeat protein 5, WD repeat-containing protein 5, WD repeat-containing protein BIG-3, WDR 5, Wdr5, WDR5_HUMAN,
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Anwendungsbeschreibung:
WDR5 polyclonal antibody detects endogenous levels of WDR5 protein.
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