Recombinant fusion protein of human GPM6A(NP_005268.1).
Konjugation:
Unconjugated
Alternative Synonym:
GPM6A,GPM6,M6A
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs, enhances internalization and recycling of mu-type opioid receptor.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB,1:500 - 1:2000
Anwendungsbeschreibung:
Unmodification
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
