Component of gems 2, Gem (nuclear organelle) associated protein 2, Gem associated protein 2, GEMI2_HUMAN, Gemin-2, gemin2, SIP 1, SIP-1, SIP1, SIP1 delta, SIP1-delta, SMN interacting protein 1, SMN interacting protein 1 delta, SMN-interacting protein 1, Survival interacting protein 1, Survival of motor neuron protein interacting protein 1, Survival of motor neuron protein-interacting protein 1,
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB: 1:500~1:2000 IHC/IF: 1:50~1:200
Anwendungsbeschreibung:
GEMIN2 polyclonal antibody detects endogenous levels of GEMIN2 protein.
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