URM1 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: URM1 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS75471
• Hersteller Artikelnummer: BS75471
• Alternativnummer: BWT-BS75471-50UL,BWT-BS75471-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Mouse, Rat
• Immunogen: Recombinant fusion protein of human URM1(NP_001252511.1).
• Konjugation: Unconjugated
• Alternative Synonym: URM1,C9orf74

Produktbeschreibung

Acts as a sulfur carrier required for 2-thiolation of mcm(5S(2U at tRNA wobble positions of cytosolic tRNA(Lys, tRNA(Glu and tRNA(Gln. Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5S(2U. Also acts as a ubiquitin-like protein (UBL that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

Produkteigenschaften

• Molekulargewicht: 11kDa
• UniProt: Q9BTM9
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100
• Anwendungsbeschreibung: Unmodification