CHN2 polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS79220
Artikelname: CHN2 polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS79220
Hersteller Artikelnummer: BS79220
Alternativnummer: BWT-BS79220-50UL,BWT-BS79220-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse
Immunogen: Recombinant fusion protein of human CHN2(NP_004058.1).
Konjugation: Unconjugated
Alternative Synonym: CHN2,ARHGAP3,BCH,CHN2-3,RHOGAP3
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants.
Molekulargewicht: 54kDa
UniProt: P52757
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB,1:200 - 1:2000
Anwendungsbeschreibung: Unmodification