KIAA1429 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: KIAA1429 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS79993
• Hersteller Artikelnummer: BS79993
• Alternativnummer: BWT-BS79993-50UL,BWT-BS79993-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Recombinant fusion protein of human KIAA1429(NP_056311.2).
• Konjugation: Unconjugated
• Alternative Synonym: KIAA1429,MSTP054,fSAP121,VIRMA

Produktbeschreibung

Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3-UTR near the stop codon correlating with alternative polyadenylation (APA.

Produkteigenschaften

• Molekulargewicht: 210KDa
• UniProt: Q69YN4
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:100
• Anwendungsbeschreibung: Unmodification