Inhibin beta A (INHBA) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS8500
Hersteller Artikelnummer:
BS8500
Alternativnummer:
BWT-BS8500-50UL,BWT-BS8500-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Recombinant fusion protein of human beta A (INHBA)(NP_002183.1).
Konjugation:
Unconjugated
Alternative Synonym:
INHBA,EDF,FRP
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200
Anwendungsbeschreibung:
Polyclonal Antibodies
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
