Phospho-Raf1 (Ser259) polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Phospho-Raf1 (Ser259) polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BZ16727
• Hersteller Artikelnummer: BZ16727
• Alternativnummer: BWT-BZ16727-50UL,BWT-BZ16727-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human Phospho-Raf1 (S259)
• Konjugation: Unconjugated
• Alternative Synonym: RAF1, RAF, RAF proto-oncogene serine/threonine-protein kinase, Proto-oncogene c-RAF, cRaf, Raf-1

Produktbeschreibung

Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.

Produkteigenschaften

• Molekulargewicht: Calculated MW: 73 kDa, Observed MW: 73 kDa
• UniProt: P04049
• Reinheit: Affinity Purified
• Formulierung: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1/500-1/1000 IHC: 1/50-1/100
• Anwendungsbeschreibung: IgG