Securin polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BZ16895
Artikelname: Securin polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BZ16895
Hersteller Artikelnummer: BZ16895
Alternativnummer: BWT-BZ16895-50UL,BWT-BZ16895-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, IHC-P, IP, WB
Spezies Reaktivität: Human
Immunogen: A synthesized peptide derived from human Securin
Konjugation: Unconjugated
Alternative Synonym: PTTG1, EAP1, PTTG, TUTR1, Securin, Esp1-associated protein, Pituitary tumor-transforming gene 1 protein, Tumor-transforming protein 1, hPTTG
Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
Molekulargewicht: Calculated MW: 22 kDa, Observed MW: 28 kDa
UniProt: O95997
Reinheit: Affinity Purified
Formulierung: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Verdünnung: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Anwendungsbeschreibung: IgG