TNF Receptor 2 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: TNF Receptor 2 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BZ16979
• Hersteller Artikelnummer: BZ16979
• Alternativnummer: BWT-BZ16979-50UL,BWT-BZ16979-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC-Fr, IHC-P, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthetic peptide of human TNF Receptor II
• Konjugation: Unconjugated
• Alternative Synonym: CD120b, p75 TNF receptor, p80 TNF alpha receptor, Soluble TNFR1B variant 1, TBP-2, TBPII, TNF R75, TNFBR, TNFR-II, TNFR1B, TNFR2, TNFR80, TNFRII, Tnfrsf1b

Produktbeschreibung

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Produkteigenschaften

• Molekulargewicht: Calculated MW: 48 kDa, Observed MW: 65 kDa
• UniProt: P20333
• Reinheit: Affinity Purified
• Formulierung: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Anwendungsbeschreibung

• Application Verdünnung: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
• Anwendungsbeschreibung: IgG