JAK2 (7H5) monoclonal antibody, Unconjugated, Mouse

Produktübersicht

• Artikelname: JAK2 (7H5) monoclonal antibody, Unconjugated, Mouse
• Artikelnummer: BWT-MB3306
• Hersteller Artikelnummer: MB3306
• Alternativnummer: BWT-MB3306-50UL,BWT-MB3306-100UL
• Hersteller: Bioworld Technology
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC-P
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic peptide conjugated to KLH.
• Konjugation: Unconjugated
• Alternative Synonym: JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2

Produktbeschreibung

Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Produkteigenschaften

• UniProt: O60674
• Reinheit: Affinity Purified
• Formulierung: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Anwendungsbeschreibung

• Application Verdünnung: IHC: 1/50-1/100
• Anwendungsbeschreibung: IgG1