PI3 Kinase p85 alpha (3H5) monoclonal antibody, Unconjugated, Mouse

Produktübersicht

• Artikelname: PI3 Kinase p85 alpha (3H5) monoclonal antibody, Unconjugated, Mouse
• Artikelnummer: BWT-MB3330
• Hersteller Artikelnummer: MB3330
• Alternativnummer: BWT-MB3330-50UL,BWT-MB3330-100UL
• Hersteller: Bioworld Technology
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Purified recombinant protein expressed in E.coli.
• Konjugation: Unconjugated
• Alternative Synonym: PIK3R1, GRB1, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha

Produktbeschreibung

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Produkteigenschaften

• Molekulargewicht: Calculated MW: 84 kDa, Observed MW: 84 kDa
• UniProt: P27986
• Reinheit: Affinity Purified
• Formulierung: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1/500-1/1000 IHC: 1/50-1/100
• Anwendungsbeschreibung: IgG1