Full length human recombinant protein of human IFIT3 (NP_001540) produced in HEK293T cell.
Konjugation:
Unconjugated
Alternative Synonym:
Gem-associated protein 2, Gemin-2, Component of gems 2, Survival of motor neuron protein-interacting protein 1 (SMN-interacting protein 1), GEMIN2, SIP1
IFIT3 (Interferon-induced protein with tetratricopeptide repeats 3, Retinoic acid-induced gene G protein (RIG-G)) is part of the IFIT family of interferon-stimulating genes known for their antiviral properties (1,2). IFIT3 is widely expressed in T cells, B cells, plasmacytoid and myeloid dendritic cells, neurons, and kidney cells (3,4). In response to RNA viral infection, IFIT3 regulates IRF3 activation through interaction with TBK1 and MAVS on the mitochondrion (5). IFIT3 also interacts with IFIT1, leading to inhibitory activity against viral RNA lacking the 2'-O-methylation in the cap structure (6).
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB 1:2000, IF 1:100, Flow 1:100
Anwendungsbeschreibung:
IgG1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
