Full length human recombinant protein of human SSSCA1 (NP_006387) produced in HEK293T cell.
Konjugation:
Unconjugated
Alternative Synonym:
Protein ZNRD2, Autoantigen p27, Sjoegren syndrome/scleroderma autoantigen 1, Zinc ribbon domain-containing protein 2, ZNRD2, SSSCA1
SSSCA1 (sjogren syndrome/scleroderma autoantigen 1), also known as p27,is a 199 amino acid protein that may play a role in mitosis. Considered a centromere-associated protein, SSSCA1 may induce anti-centromere antibodies. SSSCA1 is phosphorylated upon DNA damage by ATM or ATR. The gene encoding SSSCA1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB 1:2000, IF 1:100, FLOW 1:100, IHC: 1:150
Anwendungsbeschreibung:
IgG1
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