Mammaglobin A monoclonal antibody, Unconjugated, Mouse
Artikelnummer:
BWT-MB66078
Hersteller Artikelnummer:
MB66078
Alternativnummer:
BWT-MB66078-50UL,BWT-MB66078-100UL
Hersteller:
Bioworld Technology
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
KLH-conjugated synthetic peptide encompassing a sequence within human Mammaglobin A. The exact sequence is proprietary.
Konjugation:
Unconjugated
Alternative Synonym:
MGB1, UGB2, Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2
Secretoglobins (also called Lipophilins or Mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of Mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B (also designated MGB2, Lipophilin C, LPHC, UGB3 and SCGB2A2) is a reliable diagnostic marker for breast tumors.
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Application Verdünnung:
IHC (1/100 - 1/300)
Anwendungsbeschreibung:
Recognizes endogenous levels of Mammaglobin A protein.
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