PMEL monoclonal antibody, Unconjugated, Mouse

Artikelnummer: BWT-MB66143
Artikelname: PMEL monoclonal antibody, Unconjugated, Mouse
Artikelnummer: BWT-MB66143
Hersteller Artikelnummer: MB66143
Alternativnummer: BWT-MB66143-50UL,BWT-MB66143-100UL
Hersteller: Bioworld Technology
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human PMEL. The exact sequence is proprietary.
Konjugation: Unconjugated
Alternative Synonym: D12S53E, PMEL17, SILV, Melanocyte protein PMEL, ME20-M, ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog
PMEL/Melanoma gp100 is a type 1 transmembrane glycoprotein primarily expressed in pigment cells of the skin and eye, and overexpressed in more than 75% of human melanomas . It is involved in the transformation of melanosomes from stage I to stage II, for
Molekulargewicht: ~ 70 kDa
UniProt: P40967
Reinheit: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Application Verdünnung: IHC (1/100 - 1/300)
Anwendungsbeschreibung: Recognizes endogenous levels of PMEL protein.