Androgen Receptor monoclonal antibody, Unconjugated, Mouse

Artikelnummer: BWT-MB66147
Artikelname: Androgen Receptor monoclonal antibody, Unconjugated, Mouse
Artikelnummer: BWT-MB66147
Hersteller Artikelnummer: MB66147
Alternativnummer: BWT-MB66147-50UL,BWT-MB66147-100UL
Hersteller: Bioworld Technology
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human Androgen Receptor. The exact sequence is proprietary.
Konjugation: Unconjugated
Alternative Synonym: DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding . This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer
Molekulargewicht: ~ 115 kDa
UniProt: P10275
Reinheit: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Application Verdünnung: WB (1/500 - 1/1000), IHC (1/100 - 1/300)
Anwendungsbeschreibung: Recognizes endogenous levels of Androgen Receptor protein.