PP1 alpha monoclonal antibody, Unconjugated, Mouse

Produktübersicht

• Artikelname: PP1 alpha monoclonal antibody, Unconjugated, Mouse
• Artikelnummer: BWT-MB66487
• Hersteller Artikelnummer: MB66487
• Alternativnummer: BWT-MB66487-50UL,BWT-MB66487-100UL
• Hersteller: Bioworld Technology
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Purified recombinant human PPP1A protein fragments expressed in E.coli.
• Konjugation: Unconjugated
• Alternative Synonym: PPP1A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A

Produktbeschreibung

Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1alpha, PP1delta, PP1gamma1 and PP1gamma2 . Involvement in cell cycle regulation is one of the biological functions of PP1 . It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis . A cell cycle-dependent phosphorylation at Thr320 of PP1alpha by cdc2 kinase inhibits PP1alpha activity .

Produkteigenschaften

• Molekulargewicht: ~ 38 kDa
• UniProt: P62136
• Reinheit: The antibody was purified by immunogen affinity chromatography.
• Formulierung: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Anwendungsbeschreibung

• Application Verdünnung: WB (1/500 - 1/1000), IHC (1/50 - 1/100), IF/ICC (1/50 - 1/100)
• Anwendungsbeschreibung: Recognizes endogenous levels of PP1 alpha protein.