KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LYPD6B. The exact sequence is proprietary.
Konjugation:
Unconjugated
Alternative Synonym:
Ly6/PLAUR domain-containing protein 6B
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh, has no effect on alpha-7 homomeric nAChRs, modulates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
