Recombinant fusion protein of human ATG4C. The exact sequence is proprietary.
Konjugation:
Unconjugated
Alternative Synonym:
APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C
Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUT like 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase),APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee,canine, bovine, mouse, rat, chicken and zebrafish. Atg4C is highly expressedin skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Func tioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP.Atg4C is also inhibited by N-ethylmaleimide.
