Recombinant fusion protein of human Erbin. The exact sequence is proprietary.
Konjugation:
Unconjugated
Alternative Synonym:
ERBIN, KIAA1225, LAP2, Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, Erbin
Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated Tyr-1248 of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion.