Recombinant fusion protein of human Makorin-2. The exact sequence is proprietary.
Konjugation:
Unconjugated
Alternative Synonym:
RNF62, Probable E3 ubiquitin-protein ligase makorin-2, RING finger protein 62
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses (By similarity). Plays a role in the regulation of spermiation and in male fertility (By similarity).
