KLH-conjugated synthetic peptide of human PLM (pS68). The exact sequence is proprietary.
Konjugation:
Unconjugated
Alternative Synonym:
PLM, Phospholemman, FXYD domain-containing ion transport regulator 1
Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na+ out of the cell and K+ into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone.
