Recombinant Human B-Cell Maturation Antigen (rHuBCMA)

Produktübersicht

• Artikelname: Recombinant Human B-Cell Maturation Antigen (rHuBCMA)
• Artikelnummer: BWT-PR1005
• Hersteller Artikelnummer: PR1005
• Alternativnummer: BWT-PR1005-5UG,BWT-PR1005-20UG,BWT-PR1005-1.0MG
• Hersteller: Bioworld Technology
• Kategorie: Proteine/Peptide

Produktbeschreibung

BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain.

Produkteigenschaften

• Molekulargewicht: Approximately 5.3 KDa, a single non-glycosylated polypeptide chain containing 50 amino acids.
• Quelle: Escherichia coli.
• Reinheit: >98% by SDS-PAGE and HPLC analyses.
• Formulierung: Sterile Filtered White lyophilized (freeze-dried) powder.
• Sequenz: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
• Formel: Lyophilized from a 0.2µm filtered concentrated solution in 30% acetonitrile, 0.1% TFA.

Anwendungsbeschreibung

• Anwendungsbeschreibung: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20C. Further dilutions should be made in appropriate buffered solutions.