TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is a potent CXCR7 agonist with an EC50 of 350 nM for recruiting beta-arrestin 2 to CXCR7. TC14012 has anti-HIV activity and anti-cancer activity.
Molekulargewicht:
2066.4
Reinheit:
>98% (HPLC)
CAS Nummer:
[368874-34-4]
Formel:
C90H140N34O19S2
Target-Kategorie:
CXCR
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