inhibit, Gomisin G, HIV Protease, HIV, HIVProtease, Human immunodeficiency virus, Inhibitor, CYP2C9
Gomisin G is a natural lignan with potent in vitro anti-HIV-1 activity, demonstrating an EC50 of 0.006 µg/mL and a high therapeutic index. It serves as a substrate for CYP2C9 and is a compound of interest for virology and drug metabolism research.