Mavorixafor (AMD-070) is a potent and selective CXCR4 antagonist with a 13 nM IC50 for receptor binding. It effectively blocks T-tropic HIV-1 replication in vitro, showing IC50 values of 1 nM and 9 nM in MT-4 cells and PBMCs, respectively. Its research applications extend to oncology and immunology, including studies on cancer metastasis and stem cell mobilization.