chymase, BAY 1142524, BAY1142524, BAY-1142524, Fulacimstat, Inhibitor, inhibit
Fulacimstat (BAY1142524) is a potent and selective chymase inhibitor, demonstrating IC50 values of 3 nM and 4 nM against hamster and human enzymes, respectively. This small molecule is a valuable research tool for investigating chymase roles in cardiovascular and fibrotic diseases in both in vitro and in vivo experimental models.